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Quantification of mitochondrial DNA copy number in suspected cancer patients by a well optimized ddPCR method

Changes in mitochondrial DNA (mtDNA) content is a useful clinical biomarker for various diseases, however results are controversial as several analytical factors can affect measurement of mtDNA. MtDNA is often quantified by taking ratio between a target mitochondrial gene and a reference nuclear gen...

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Detalles Bibliográficos
Autores principales:	Memon, Ashfaque A., Zöller, Bengt, Hedelius, Anna, Wang, Xiao, Stenman, Emelie, Sundquist, Jan, Sundquist, Kristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634817/ https://www.ncbi.nlm.nih.gov/pubmed/29021970 http://dx.doi.org/10.1016/j.bdq.2017.08.001

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