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Metastatic pathway and the microvascular and physicochemical microenvironments of human melanoma xenografts

BACKGROUND: Malignant melanoma of the skin can metastasize through blood vessels and lymphatics. The primary tumor develops a vascular microenvironment characterized by abnormal blood vessels and lymphatics and a physicochemical microenvironment characterized by low oxygen tension, regions with hypo...

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Detalles Bibliográficos
Autores principales: Huang, Ruixia, Andersen, Lise Mari K., Rofstad, Einar K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634823/
https://www.ncbi.nlm.nih.gov/pubmed/29017512
http://dx.doi.org/10.1186/s12967-017-1307-4