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Contextual tumor suppressor function of T cell death-associated gene 8 (TDAG8) in hematological malignancies
BACKGROUND: Extracellular acidosis is a condition found within the tumor microenvironment due to inadequate blood perfusion, hypoxia, and altered tumor cell metabolism. Acidosis has pleiotropic effects on malignant progression; therefore it is essential to understand how acidosis exerts its diverse...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634876/ https://www.ncbi.nlm.nih.gov/pubmed/29017562 http://dx.doi.org/10.1186/s12967-017-1305-6 |