The nuclear receptor ERβ engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading

BACKGROUND: The RNA-binding protein Argonaute 2 (AGO2) is a key effector of RNA-silencing pathways It exerts a pivotal role in microRNA maturation and activity and can modulate chromatin remodeling, transcriptional gene regulation and RNA splicing. Estrogen receptor beta (ERβ) is endowed with oncosu...

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Detalles Bibliográficos
Autores principales: Tarallo, Roberta, Giurato, Giorgio, Bruno, Giuseppina, Ravo, Maria, Rizzo, Francesca, Salvati, Annamaria, Ricciardi, Luca, Marchese, Giovanna, Cordella, Angela, Rocco, Teresa, Gigantino, Valerio, Pierri, Biancamaria, Cimmino, Giovanni, Milanesi, Luciano, Ambrosino, Concetta, Nyman, Tuula A., Nassa, Giovanni, Weisz, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634881/
https://www.ncbi.nlm.nih.gov/pubmed/29017520
http://dx.doi.org/10.1186/s13059-017-1321-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634881/
https://www.ncbi.nlm.nih.gov/pubmed/29017520
http://dx.doi.org/10.1186/s13059-017-1321-0

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