Mechanistic Evaluation and Translational Signature of Gemcitabine-induced Chemoresistance by Quantitative Phosphoproteomics Analysis with iTRAQ Labeling Mass Spectrometry

One of the main causations of the poor prognosis of pancreatic cancer is the lack of effective chemotherapies. Gemcitabine is a widely used chemotherapeutic drug, but limited therapeutic efficacy is achieved due to chemoresistance. Recent studies demonstrated that the presence of cancer stem cells m...

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Detalles Bibliográficos
Autores principales: Duan, Qingke, Zhao, Hengqiang, Zhang, Zhengle, Li, Hehe, Wu, Heshui, Shen, Qiang, Wang, Chunyou, Yin, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634998/
https://www.ncbi.nlm.nih.gov/pubmed/29018223
http://dx.doi.org/10.1038/s41598-017-13330-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634998/
https://www.ncbi.nlm.nih.gov/pubmed/29018223
http://dx.doi.org/10.1038/s41598-017-13330-2

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