DUSP5 functions as a feedback regulator of TNFα-induced ERK1/2 dephosphorylation and inflammatory gene expression in adipocytes

Adipose tissue inflammation is a central pathological element that regulates obesity-mediated insulin resistance and type II diabetes. Evidence demonstrates that extracellular signal-regulated kinase (ERK 1/2) activation (i.e. phosphorylation) links tumor necrosis factor α (TNFα) to pro-inflammatory...

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Detalles Bibliográficos
Autores principales: Habibian, Justine S., Jefic, Mitra, Bagchi, Rushita A., Lane, Robert H., McKnight, Robert A., McKinsey, Timothy A., Morrison, Ron F., Ferguson, Bradley S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635013/
https://www.ncbi.nlm.nih.gov/pubmed/29018280
http://dx.doi.org/10.1038/s41598-017-12861-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635013/
https://www.ncbi.nlm.nih.gov/pubmed/29018280
http://dx.doi.org/10.1038/s41598-017-12861-y

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