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The loss of P2X7 receptor expression leads to increase intestinal glucose transit and hepatic steatosis

In intestinal epithelial cells (IEC), it was reported that the activation of the P2X7 receptor leads to the internalization of the glucose transporter GLUT2, which is accompanied by a reduction of IEC capacity to transport glucose. In this study, we used P2rx7 (−/−) mice to decipher P2X7 functions i...

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Detalles Bibliográficos
Autores principales: Arguin, Guillaume, Bourzac, Jean-François, Placet, Morgane, Molle, Caroline M., Paquette, Michel, Beaudoin, Jean-François, Rousseau, Jacques A., Lecomte, Roger, Plourde, Mélanie, Gendron, Fernand-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635021/
https://www.ncbi.nlm.nih.gov/pubmed/29018292
http://dx.doi.org/10.1038/s41598-017-13300-8