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The loss of P2X7 receptor expression leads to increase intestinal glucose transit and hepatic steatosis
In intestinal epithelial cells (IEC), it was reported that the activation of the P2X7 receptor leads to the internalization of the glucose transporter GLUT2, which is accompanied by a reduction of IEC capacity to transport glucose. In this study, we used P2rx7 (−/−) mice to decipher P2X7 functions i...
Autores principales: | Arguin, Guillaume, Bourzac, Jean-François, Placet, Morgane, Molle, Caroline M., Paquette, Michel, Beaudoin, Jean-François, Rousseau, Jacques A., Lecomte, Roger, Plourde, Mélanie, Gendron, Fernand-Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635021/ https://www.ncbi.nlm.nih.gov/pubmed/29018292 http://dx.doi.org/10.1038/s41598-017-13300-8 |
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