Variant surface glycoprotein density defines an immune evasion threshold for African trypanosomes undergoing antigenic variation

Trypanosoma brucei is a protozoan parasite that evades its host’s adaptive immune response by repeatedly replacing its dense variant surface glycoprotein (VSG) coat from its large genomic VSG repertoire. While the mechanisms regulating VSG gene expression and diversification have been examined exten...

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Detalles Bibliográficos
Autores principales: Pinger, Jason, Chowdhury, Shanin, Papavasiliou, F. Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635023/
https://www.ncbi.nlm.nih.gov/pubmed/29018220
http://dx.doi.org/10.1038/s41467-017-00959-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635023/
https://www.ncbi.nlm.nih.gov/pubmed/29018220
http://dx.doi.org/10.1038/s41467-017-00959-w

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