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Variant surface glycoprotein density defines an immune evasion threshold for African trypanosomes undergoing antigenic variation
Trypanosoma brucei is a protozoan parasite that evades its host’s adaptive immune response by repeatedly replacing its dense variant surface glycoprotein (VSG) coat from its large genomic VSG repertoire. While the mechanisms regulating VSG gene expression and diversification have been examined exten...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635023/ https://www.ncbi.nlm.nih.gov/pubmed/29018220 http://dx.doi.org/10.1038/s41467-017-00959-w |