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Tumor-Penetrating Delivery of siRNA against TNFα to Human Vestibular Schwannomas

Vestibular schwannoma (VS) is the most common tumor of the cerebellopontine angle, and it typically presents with sensorineural hearing loss. The genomic landscape of schwannoma is complex and many of the molecules implicated in VS pathogenesis represent targets not amenable to antibody-based or sma...

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Detalles Bibliográficos
Autores principales: Ren, Yin, Sagers, Jessica E., Landegger, Lukas D., Bhatia, Sangeeta N., Stankovic, Konstantina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635039/
https://www.ncbi.nlm.nih.gov/pubmed/29018206
http://dx.doi.org/10.1038/s41598-017-13032-9