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D-serine released by astrocytes in brainstem regulates breathing response to CO(2) levels

Central chemoreception is essential for adjusting breathing to physiological demands, and for maintaining CO(2) and pH homeostasis in the brain. CO(2)-induced ATP release from brainstem astrocytes stimulates breathing. NMDA receptor (NMDAR) antagonism reduces the CO(2)-induced hyperventilation by un...

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Detalles Bibliográficos
Autores principales: Beltrán-Castillo, S., Olivares, M. J., Contreras, R. A., Zúñiga, G., Llona, I., von Bernhardi, R., Eugenín, J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635109/
https://www.ncbi.nlm.nih.gov/pubmed/29018191
http://dx.doi.org/10.1038/s41467-017-00960-3