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D-serine released by astrocytes in brainstem regulates breathing response to CO(2) levels
Central chemoreception is essential for adjusting breathing to physiological demands, and for maintaining CO(2) and pH homeostasis in the brain. CO(2)-induced ATP release from brainstem astrocytes stimulates breathing. NMDA receptor (NMDAR) antagonism reduces the CO(2)-induced hyperventilation by un...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635109/ https://www.ncbi.nlm.nih.gov/pubmed/29018191 http://dx.doi.org/10.1038/s41467-017-00960-3 |