Cargando…

6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury

Necroptosis is a programmed cell death pathway that has been shown to be of central pathophysiological relevance in multiple disorders (hepatitis, brain and cardiac ischemia, pancreatitis, viral infection and inflammatory diseases). Necroptosis is driven by two serine threonine kinases, RIPK1 (Recep...

Descripción completa

Detalles Bibliográficos
Autores principales: Delehouzé, C., Leverrier-Penna, S., Le Cann, F., Comte, A., Jacquard-Fevai, M., Delalande, O., Desban, N., Baratte, B., Gallais, I., Faurez, F., Bonnet, M. C., Hauteville, M., Goekjian, P. G., Thuillier, R., Favreau, F., Vandenabeele, P., Hauet, T., Dimanche-Boitrel, M. T., Bach, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635128/
https://www.ncbi.nlm.nih.gov/pubmed/29018243
http://dx.doi.org/10.1038/s41598-017-12788-4