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mTOR/Raptor signaling is critical for skeletogenesis in mice through the regulation of Runx2 expression

The mammalian target of rapamycin (mTOR)/regulatory-associated protein of mTOR (Raptor) pathway transmits and integrates different signals including growth factors, nutrients, and energy metabolism. Nearly all these signals have been found to play roles in skeletal biology. However, the contribution...

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Detalles Bibliográficos
Autores principales: Dai, Qinggang, Xu, Zhan, Ma, Xuhui, Niu, Ningning, Zhou, Siru, Xie, Furong, Jiang, Lingyong, Wang, Jun, Zou, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635215/
https://www.ncbi.nlm.nih.gov/pubmed/28686577
http://dx.doi.org/10.1038/cdd.2017.110