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High mobility group A1 protein modulates autophagy in cancer cells

High Mobility Group A1 (HMGA1) is an architectural chromatin protein whose overexpression is a feature of malignant neoplasias with a causal role in cancer initiation and progression. HMGA1 promotes tumor growth by several mechanisms, including increase of cell proliferation and survival, impairment...

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Detalles Bibliográficos
Autores principales: Conte, Andrea, Paladino, Simona, Bianco, Gaia, Fasano, Dominga, Gerlini, Raffaele, Tornincasa, Mara, Renna, Maurizio, Fusco, Alfredo, Tramontano, Donatella, Pierantoni, Giovanna Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635219/
https://www.ncbi.nlm.nih.gov/pubmed/28777374
http://dx.doi.org/10.1038/cdd.2017.117