Interaction of galectin-3 with MUC1 on cell surface promotes EGFR dimerization and activation in human epithelial cancer cells

Epidermal growth factor receptor (EGFR) is an important regulator of epithelial cell growth and survival in normal and cancerous tissues and is a principal therapeutic target for cancer treatment. EGFR is associated in epithelial cells with the heavily glycosylated transmembrane mucin protein MUC1,...

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Detalles Bibliográficos
Autores principales: Piyush, Tushar, Chacko, Anisha R, Sindrewicz, Paulina, Hilkens, John, Rhodes, Jonathan M, Yu, Lu-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635220/
https://www.ncbi.nlm.nih.gov/pubmed/28731466
http://dx.doi.org/10.1038/cdd.2017.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635220/
https://www.ncbi.nlm.nih.gov/pubmed/28731466
http://dx.doi.org/10.1038/cdd.2017.119

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