Cargando…

Interaction of galectin-3 with MUC1 on cell surface promotes EGFR dimerization and activation in human epithelial cancer cells

Epidermal growth factor receptor (EGFR) is an important regulator of epithelial cell growth and survival in normal and cancerous tissues and is a principal therapeutic target for cancer treatment. EGFR is associated in epithelial cells with the heavily glycosylated transmembrane mucin protein MUC1,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Piyush, Tushar, Chacko, Anisha R, Sindrewicz, Paulina, Hilkens, John, Rhodes, Jonathan M, Yu, Lu-Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635220/ https://www.ncbi.nlm.nih.gov/pubmed/28731466 http://dx.doi.org/10.1038/cdd.2017.119

Ejemplares similares

MUC1 O-glycosylation contributes to anoikis resistance in epithelial cancer cells
por: Piyush, Tushar, et al.
Publicado: (2017)

Galectin-3 Is a Natural Binding Ligand of MCAM (CD146, MUC18) in Melanoma Cells and Their Interaction Promotes Melanoma Progression
por: Pang, Yaoyu, et al.
Publicado: (2022)

Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis
por: Zhao, Qicheng, et al.
Publicado: (2010)

MUC1 extracellular domain confers resistance of epithelial cancer cells to anoikis
por: Zhao, Q, et al.
Publicado: (2014)

Interaction of the Oncofetal Thomsen–Friedenreich Antigen with Galectins in Cancer Progression and Metastasis
por: Sindrewicz, Paulina, et al.
Publicado: (2016)

Intrinsic tryptophan fluorescence spectroscopy reliably determines galectin-ligand interactions
por: Sindrewicz, Paulina, et al.
Publicado: (2019)

Galectin-3 and Epithelial MUC1 Mucin—Interactions Supporting Cancer Development
por: Radziejewska, Iwona
Publicado: (2023)

Chemically modified, non-anticoagulant heparin derivatives are potent galectin-3 binding inhibitors and inhibit circulating galectin-3-promoted metastasis
por: Duckworth, Carrie A., et al.
Publicado: (2015)

E-cadherin dynamics is regulated by galectin-7 at epithelial cell surface
por: Advedissian, Tamara, et al.
Publicado: (2017)

Downregulation of cell surface CA125/MUC16 induces epithelial-to-mesenchymal transition and restores EGFR signalling in NIH:OVCAR3 ovarian carcinoma cells
por: Comamala, M, et al.
Publicado: (2011)

MUC1 Contributes to BPDE-Induced Human Bronchial Epithelial Cell Transformation through Facilitating EGFR Activation
por: Xu, Xiuling, et al.
Publicado: (2012)

LPS Increases MUC5AC by TACE/TGF-α/EGFR Pathway in Human Intrahepatic Biliary Epithelial Cell
por: Liu, Zipei, et al.
Publicado: (2013)

MUC13 Cell Surface Mucin Limits Salmonella Typhimurium Infection by Protecting the Mucosal Epithelial Barrier
por: McGuckin, Michael A., et al.
Publicado: (2023)

Galectins in epithelial functions
por: Viguier, Mireille, et al.
Publicado: (2014)

MUC1-ARF—A Novel MUC1 Protein That Resides in the Nucleus and Is Expressed by Alternate Reading Frame Translation of MUC1 mRNA
por: Chalick, Michael, et al.
Publicado: (2016)

Differential Muc2 and Muc5ac secretion by stimulated guinea pig tracheal epithelial cells in vitro
por: Chorley, Brian N, et al.
Publicado: (2006)

Upregulation of cell-surface mucin MUC15 in human nasal epithelial cells upon influenza A virus infection
por: Chen, Zhuang Gui, et al.
Publicado: (2019)

Appearance of peanut agglutinin in the blood circulation after peanut ingestion promotes endothelial secretion of metastasis-promoting cytokines
por: Wang, Weikun, et al.
Publicado: (2021)

Comparison of the Transmembrane Mucins MUC1 and MUC16 in Epithelial Barrier Function
por: Gipson, Ilene K., et al.
Publicado: (2014)

Epidemic Keratoconjunctivitis-Causing Adenoviruses Induce MUC16 Ectodomain Release To Infect Ocular Surface Epithelial Cells
por: Menon, Balaraj B., et al.
Publicado: (2016)

Regulation of episialin/MUC1 expression in breast carcinomas: a complex interplay between stimulatory and inhibitory factors
por: Gaemers, I, et al.
Publicado: (2001)

Mometasone Furoate Suppresses PMA-Induced MUC-5AC and MUC-2 Production in Human Airway Epithelial Cells
por: Poachanukoon, Orapan, et al.
Publicado: (2017)

MUC1 stimulates EGFR expression and function in endometrial cancer
por: Engel, Brian J., et al.
Publicado: (2016)

Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7
por: Pham, N. T. Hang, et al.
Publicado: (2021)

Cell membrane-anchored MUC4 promotes tumorigenicity in epithelial carcinomas
por: Xia, Pengpeng, et al.
Publicado: (2016)

Endoplasmic Reticulum Stress Induces MUC5AC and MUC5B Expression in Human Nasal Airway Epithelial Cells
por: Kim, Min Han, et al.
Publicado: (2019)

Effect of Korean Red Ginseng and Rg3 on Asian Sand Dust-Induced MUC5AC, MUC5B, and MUC8 Expression in Bronchial Epithelial Cells
por: Shin, Seung-Heon, et al.
Publicado: (2021)

Exploration of Galectin Ligands Displayed on Gram-Negative Respiratory Bacterial Pathogens with Different Cell Surface Architectures
por: Campanero-Rhodes, María A., et al.
Publicado: (2021)

Galectin-3 is a non-classic RNA binding protein that stabilizes the mucin MUC4 mRNA in the cytoplasm of cancer cells
por: Coppin, Lucie, et al.
Publicado: (2017)

Inhibiting EGFR Dimerization Using Triazolyl-Bridged Dimerization Arm Mimics
por: Hanold, Laura E., et al.
Publicado: (2015)

Investigating Cell Surface Galectin-Mediated Cross-Linking on Glycoengineered Cells
por: Belardi, Brian, et al.
Publicado: (2012)

Positive feedback of the amphiregulin-EGFR-ERK pathway mediates PM2.5 from wood smoke-induced MUC5AC expression in epithelial cells
por: Huang, Lingmei, et al.
Publicado: (2017)

Lysophosphatidylserine Induces MUC5AC Production via the Feedforward Regulation of the TACE-EGFR-ERK Pathway in Airway Epithelial Cells in a Receptor-Independent Manner
por: Sim, Myeong Seong, et al.
Publicado: (2022)

Galectin-7 in Epithelial Homeostasis and Carcinomas
por: Advedissian, Tamara, et al.
Publicado: (2017)

Design of a peptidic inhibitor that targets the dimer interface of a prototypic galectin
por: Vladoiu, Maria Claudia, et al.
Publicado: (2015)

Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells
por: Baumlin, Nathalie, et al.
Publicado: (2023)

Significant increase in hEGF uptake is correlated with formation of EGFR dimers induced by the EGFR tyrosine kinase inhibitor gefitinib
por: He, Peng, et al.
Publicado: (2013)

Diminished milk fat secretion and premature mammary gland involution in episialin/MUC1 transgenic mice
por: Wesseling, J, et al.
Publicado: (2001)

Cell Surface Galectin-9 Expressing Th Cells Regulate Th17 and Foxp3(+) Treg Development by Galectin-9 Secretion
por: Oomizu, Souichi, et al.
Publicado: (2012)

MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition
por: Roy, Lopamudra Das, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_dg7gsqn5r5nl8bikmhaldvu1r3