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Strategies for the etiological therapy of cystic fibrosis

Etiological therapies aim at repairing the underlying cause of cystic fibrosis (CF), which is the functional defect of the cystic fibrosis transmembrane conductance regulator (CFTR) protein owing to mutations in the CFTR gene. Among these, the F508del CFTR mutation accounts for more than two thirds...

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Detalles Bibliográficos
Autores principales: Maiuri, Luigi, Raia, Valeria, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635223/
https://www.ncbi.nlm.nih.gov/pubmed/28937684
http://dx.doi.org/10.1038/cdd.2017.126