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Strategies for the etiological therapy of cystic fibrosis
Etiological therapies aim at repairing the underlying cause of cystic fibrosis (CF), which is the functional defect of the cystic fibrosis transmembrane conductance regulator (CFTR) protein owing to mutations in the CFTR gene. Among these, the F508del CFTR mutation accounts for more than two thirds...
Autores principales: | Maiuri, Luigi, Raia, Valeria, Kroemer, Guido |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635223/ https://www.ncbi.nlm.nih.gov/pubmed/28937684 http://dx.doi.org/10.1038/cdd.2017.126 |
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