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Differential Effects of Angelicin Analogues on NF-κB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells

The angelicin analogue 4,6,4′-trimethylangelicin (TMA) was recently reported as a strong inhibitor of nuclear factor-κB (NF-κB) activity and of the expression of the interleukin-8 (IL-8) gene in bronchial epithelial cells in which the inflammatory response has been challenged with P. aeruginosa, the...

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Detalles Bibliográficos
Autores principales: Lampronti, Ilaria, Manzione, Maria Giulia, Sacchetti, Gianni, Ferrari, Davide, Spisani, Susanna, Bezzerri, Valentino, Finotti, Alessia, Borgatti, Monica, Dechecchi, Maria Cristina, Miolo, Giorgia, Marzaro, Giovanni, Cabrini, Giulio, Gambari, Roberto, Chilin, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635289/
https://www.ncbi.nlm.nih.gov/pubmed/29089668
http://dx.doi.org/10.1155/2017/2389487