A Novel System for the Quantification of the ADCC Activity of Therapeutic Antibodies

Novel ADCC effector cells expressing the V-variant or F-variant of FcγRIIIa (CD16a) and firefly luciferase under the control of a chimeric promoter incorporating recognition sequences for the principal transcription factors involved in FcγRIIIa signal transduction, together with novel target cells o...

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Detalles Bibliográficos
Autores principales: Lallemand, Christophe, Liang, Feifei, Staub, Flore, Simansour, Maud, Vallette, Benoit, Huang, Lue, Ferrando-Miguel, Rosa, Tovey, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635472/
https://www.ncbi.nlm.nih.gov/pubmed/29104875
http://dx.doi.org/10.1155/2017/3908289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635472/
https://www.ncbi.nlm.nih.gov/pubmed/29104875
http://dx.doi.org/10.1155/2017/3908289

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