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A Novel System for the Quantification of the ADCC Activity of Therapeutic Antibodies
Novel ADCC effector cells expressing the V-variant or F-variant of FcγRIIIa (CD16a) and firefly luciferase under the control of a chimeric promoter incorporating recognition sequences for the principal transcription factors involved in FcγRIIIa signal transduction, together with novel target cells o...
Autores principales: | Lallemand, Christophe, Liang, Feifei, Staub, Flore, Simansour, Maud, Vallette, Benoit, Huang, Lue, Ferrando-Miguel, Rosa, Tovey, Michael G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635472/ https://www.ncbi.nlm.nih.gov/pubmed/29104875 http://dx.doi.org/10.1155/2017/3908289 |
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