DNA damage response and cancer therapeutics through the lens of the Fanconi Anemia DNA repair pathway

Fanconi Anemia (FA) is a rare, inherited genomic instability disorder, caused by mutations in genes involved in the repair of interstrand DNA crosslinks (ICLs). The FA signaling network contains a unique nuclear protein complex that mediates the monoubiquitylation of the FANCD2 and FANCI heterodimer...

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Detalles Bibliográficos
Autores principales: Bhattacharjee, Sonali, Nandi, Saikat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635482/
https://www.ncbi.nlm.nih.gov/pubmed/29017571
http://dx.doi.org/10.1186/s12964-017-0195-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635482/
https://www.ncbi.nlm.nih.gov/pubmed/29017571
http://dx.doi.org/10.1186/s12964-017-0195-9

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