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DNA damage response and cancer therapeutics through the lens of the Fanconi Anemia DNA repair pathway

Fanconi Anemia (FA) is a rare, inherited genomic instability disorder, caused by mutations in genes involved in the repair of interstrand DNA crosslinks (ICLs). The FA signaling network contains a unique nuclear protein complex that mediates the monoubiquitylation of the FANCD2 and FANCI heterodimer...

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Detalles Bibliográficos
Autores principales:	Bhattacharjee, Sonali, Nandi, Saikat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635482/ https://www.ncbi.nlm.nih.gov/pubmed/29017571 http://dx.doi.org/10.1186/s12964-017-0195-9

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