Luciferase shRNA Presents off-Target Effects on Voltage-Gated Ion Channels in Mouse Hippocampal Pyramidal Neurons

RNA interference (RNAi) is a straightforward approach to study gene function from the in vitro cellular level to in vivo animal behavior. Although RNAi-mediated gene knockdown has become essentially routine in neuroscience over the past ten years, off-target effects of short hairpin RNAs (shRNAs) sh...

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Detalles Bibliográficos
Autores principales: Hasegawa, Yuto, Mao, Wenjie, Saha, Sucharita, Gunner, Georgia, Kolpakova, Jenya, Martin, Gilles E., Futai, Kensuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635487/
https://www.ncbi.nlm.nih.gov/pubmed/29034317
http://dx.doi.org/10.1523/ENEURO.0186-17.2017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635487/
https://www.ncbi.nlm.nih.gov/pubmed/29034317
http://dx.doi.org/10.1523/ENEURO.0186-17.2017

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