Reconstructing cancer drug response networks using multitask learning

BACKGROUND: Translating in vitro results to clinical tests is a major challenge in systems biology. Here we present a new Multi-Task learning framework which integrates thousands of cell line expression experiments to reconstruct drug specific response networks in cancer. RESULTS: The reconstructed...

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Detalles Bibliográficos
Autores principales: Ruffalo, Matthew, Stojanov, Petar, Pillutla, Venkata Krishna, Varma, Rohan, Bar-Joseph, Ziv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635550/
https://www.ncbi.nlm.nih.gov/pubmed/29017547
http://dx.doi.org/10.1186/s12918-017-0471-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635550/
https://www.ncbi.nlm.nih.gov/pubmed/29017547
http://dx.doi.org/10.1186/s12918-017-0471-8

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