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Quinolone Resistance Reversion by Targeting the SOS Response

Suppression of the SOS response has been postulated as a therapeutic strategy for potentiating antimicrobial agents. We aimed to evaluate the impact of its suppression on reversing resistance using a model of isogenic strains of Escherichia coli representing multiple levels of quinolone resistance....

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Detalles Bibliográficos
Autores principales: Recacha, E., Machuca, J., Díaz de Alba, P., Ramos-Güelfo, M., Docobo-Pérez, F., Rodriguez-Beltrán, J., Blázquez, J., Pascual, A., Rodríguez-Martínez, J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635686/
https://www.ncbi.nlm.nih.gov/pubmed/29018116
http://dx.doi.org/10.1128/mBio.00971-17