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Limitations of Current in Vivo Mouse Models for the Study of Chikungunya Virus Pathogenesis
Chikungunya virus (CHIKV) is an arthropod-borne alphavirus that causes febrile chikungunya fever (CHIKF) in humans. This disease is debilitating and characterized by acute fever onset and chronic incapacitating polyarthralgia. CHIKF pathogenesis remains poorly defined with no approved vaccines and t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635755/ https://www.ncbi.nlm.nih.gov/pubmed/29083392 http://dx.doi.org/10.3390/medsci3030064 |