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Limitations of Current in Vivo Mouse Models for the Study of Chikungunya Virus Pathogenesis

Chikungunya virus (CHIKV) is an arthropod-borne alphavirus that causes febrile chikungunya fever (CHIKF) in humans. This disease is debilitating and characterized by acute fever onset and chronic incapacitating polyarthralgia. CHIKF pathogenesis remains poorly defined with no approved vaccines and t...

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Detalles Bibliográficos
Autores principales: Chan, Yi-Hao, Lum, Fok-Moon, Ng, Lisa F. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635755/
https://www.ncbi.nlm.nih.gov/pubmed/29083392
http://dx.doi.org/10.3390/medsci3030064