Cargando…

Limitations of Current in Vivo Mouse Models for the Study of Chikungunya Virus Pathogenesis

Chikungunya virus (CHIKV) is an arthropod-borne alphavirus that causes febrile chikungunya fever (CHIKF) in humans. This disease is debilitating and characterized by acute fever onset and chronic incapacitating polyarthralgia. CHIKF pathogenesis remains poorly defined with no approved vaccines and t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chan, Yi-Hao, Lum, Fok-Moon, Ng, Lisa F. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635755/ https://www.ncbi.nlm.nih.gov/pubmed/29083392 http://dx.doi.org/10.3390/medsci3030064

Ejemplares similares

Expanding Regulatory T Cells Alleviates Chikungunya Virus-Induced Pathology in Mice
por: Lee, Wendy W. L., et al.
Publicado: (2015)

Paradoxical Effect of Chloroquine Treatment in Enhancing Chikungunya Virus Infection
por: Roques, Pierre, et al.
Publicado: (2018)

Plasmodium co-infection protects against chikungunya virus-induced pathologies
por: Teo, Teck-Hui, et al.
Publicado: (2018)

Viperin controls chikungunya virus–specific pathogenic T cell IFNγ Th1 stimulation in mice
por: Carissimo, Guillaume, et al.
Publicado: (2019)

Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity
por: Lum, Fok-Moon, et al.
Publicado: (2018)

Mutating chikungunya virus non‐structural protein produces potent live‐attenuated vaccine candidate
por: Chan, Yi‐Hao, et al.
Publicado: (2019)

Co‐infection with Chikungunya virus alters trafficking of pathogenic CD8(+) T cells into the brain and prevents Plasmodium‐induced neuropathology
por: Teo, Teck‐Hui, et al.
Publicado: (2017)

A Review on Chikungunya Virus Epidemiology, Pathogenesis and Current Vaccine Development
por: de Lima Cavalcanti, Thaise Yasmine Vasconcelos, et al.
Publicado: (2022)

Caribbean and La Réunion Chikungunya Virus Isolates Differ in Their Capacity To Induce Proinflammatory Th1 and NK Cell Responses and Acute Joint Pathology
por: Teo, Teck-Hui, et al.
Publicado: (2015)

Role of T Cells in Chikungunya Virus Infection and Utilizing Their Potential in Anti-Viral Immunity
por: Poh, Chek Meng, et al.
Publicado: (2020)

Development of a Hamster Model for Chikungunya Virus Infection and Pathogenesis
por: Bosco-Lauth, Angela M., et al.
Publicado: (2015)

Visualization of chikungunya virus infection in vitro and in vivo
por: Zhang, Hong-Lei, et al.
Publicado: (2019)

Establishment of a Novel Primary Human Skeletal Myoblast Cellular Model for Chikungunya Virus Infection and Pathogenesis
por: Hussain, Khairunnisa’ Mohamed, et al.
Publicado: (2016)

VCP/p97 Is a Proviral Host Factor for Replication of Chikungunya Virus and Other Alphaviruses
por: Carissimo, Guillaume, et al.
Publicado: (2019)

Novel Lesions of Bones and Joints Associated with Chikungunya Virus Infection in Two Mouse Models of Disease: New Insights into Disease Pathogenesis
por: Goupil, Brad A., et al.
Publicado: (2016)

Current and Promising Antivirals Against Chikungunya Virus
por: Hucke, Friederike I. L., et al.
Publicado: (2020)

Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein
por: Kam, Yiu-Wing, et al.
Publicado: (2012)

Chikungunya in Infants and Children: Is Pathogenesis Increasing?
por: Barr, Kelli L., et al.
Publicado: (2019)

Technical challenges and limitations of current mouse models of ovarian cancer
por: Garson, Kenneth, et al.
Publicado: (2012)

A Review of Chikungunya Virus-induced Arthralgia: Clinical Manifestations, Therapeutics, and Pathogenesis
por: Goupil, Brad A., et al.
Publicado: (2016)

Human Genetic Host Factors and Its Role in the Pathogenesis of Chikungunya Virus Infection
por: Rueda, Juan C., et al.
Publicado: (2022)

Understanding the Biology and Immune Pathogenesis of Chikungunya Virus Infection for Diagnostic and Vaccine Development
por: Hakim, Mohamad S., et al.
Publicado: (2022)

Chikungunya Virus
por: Vu, David M., et al.
Publicado: (2017)

Reduced development of COVID-19 in children reveals molecular checkpoints gating pathogenesis illuminating potential therapeutics
por: Steinman, Jonathan Baruch, et al.
Publicado: (2020)

A scoping review of published literature on chikungunya virus
por: Mascarenhas, Mariola, et al.
Publicado: (2018)

Chikungunya Virus: Pathophysiology, Mechanism, and Modeling
por: Ganesan, Vaishnavi K., et al.
Publicado: (2017)

Mouse macrophage innate immune response to chikungunya virus infection
por: Kumar, Shiril, et al.
Publicado: (2012)

Chikungunya Virus in Macaques, Malaysia
por: Sam, I-Ching, et al.
Publicado: (2015)

Characterization of Chikungunya Virus Induced Host Response in a Mouse Model of Viral Myositis
por: Dhanwani, Rekha, et al.
Publicado: (2014)

Silvestrol Inhibits Chikungunya Virus Replication
por: Henss, Lisa, et al.
Publicado: (2018)

Chikungunya and Skin: Current Perspective
por: Singal, Archana
Publicado: (2017)

Current Status of Chikungunya in India
Publicado: (2021)

Characterization of Aedes aegypti Innate-Immune Pathways that Limit Chikungunya Virus Replication
por: McFarlane, Melanie, et al.
Publicado: (2014)

Chikungunya fever: Epidemiology, clinical syndrome, pathogenesis and therapy
por: Thiberville, Simon-Djamel, et al.
Publicado: (2013)

FHL1 promotes chikungunya and o’nyong-nyong virus infection and pathogenesis with implications for alphavirus vaccine design
por: Ng, Wern Hann, et al.
Publicado: (2023)

Chikungunya Virus Infection
por: Simon, Fabrice, et al.
Publicado: (2011)

Tropism of the Chikungunya Virus
por: Matusali, Giulia, et al.
Publicado: (2019)

Current Efforts in the Development of Vaccines for the Prevention of Zika and Chikungunya Virus Infections
por: Schrauf, Sabrina, et al.
Publicado: (2020)

Chikungunya Virus Diagnosis: A Review of Current Antigen Detection Methods
por: Simo, Fredy Brice Nemg, et al.
Publicado: (2023)

Seroprevalence of antibodies against chikungunya virus in Singapore resident adult population
por: Ang, Li Wei, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_7om6hh3t9c2ccs1ian2uj1avrq