Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models

The gut microbiota regulates T cell functions throughout the body. We hypothesized that intestinal bacteria impact the pathogenesis of multiple sclerosis (MS), an autoimmune disorder of the CNS and thus analyzed the microbiomes of 71 MS patients not undergoing treatment and 71 healthy controls. Alth...

Descripción completa

Detalles Bibliográficos
Autores principales: Cekanaviciute, Egle, Yoo, Bryan B., Runia, Tessel F., Debelius, Justine W., Singh, Sneha, Nelson, Charlotte A., Kanner, Rachel, Bencosme, Yadira, Lee, Yun Kyung, Hauser, Stephen L., Crabtree-Hartman, Elizabeth, Sand, Ilana Katz, Gacias, Mar, Zhu, Yunjiao, Casaccia, Patrizia, Cree, Bruce A. C., Knight, Rob, Mazmanian, Sarkis K., Baranzini, Sergio E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635915/
https://www.ncbi.nlm.nih.gov/pubmed/28893978
http://dx.doi.org/10.1073/pnas.1711235114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635915/
https://www.ncbi.nlm.nih.gov/pubmed/28893978
http://dx.doi.org/10.1073/pnas.1711235114

Ejemplares similares