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High dose teriparatide (rPTH(1-34)) therapy increases callus volume and enhances radiographic healing at 8-weeks in a massive canine femoral allograft model

Small animal studies have demonstrated significant high-dose recombinant parathyroid hormone(1-34) (rPTH(1-34)) effects on intercalary allograft healing. Towards a human adjuvant therapy to decrease non-unions, we evaluated rPTH(1-34) safety and efficacy in a clinically relevant canine femoral allog...

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Detalles Bibliográficos
Autores principales: Nishitani, Kohei, Mietus, Zachary, Beck, Christopher A., Ito, Hiromu, Matsuda, Shuichi, Awad, Hani A., Ehrhart, Nicole, Schwarz, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636088/
https://www.ncbi.nlm.nih.gov/pubmed/29020057
http://dx.doi.org/10.1371/journal.pone.0185446