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Mixtures of tense and relaxed state polymerized human hemoglobin regulate oxygen affinity and tissue construct oxygenation

Pure tense (T) and relaxed (R) quaternary state polymerized human hemoglobins (PolyhHbs) were synthesized and their biophysical properties characterized, along with mixtures of T- and R-state PolyhHbs. It was observed that the oxygen affinity of PolyhHb mixtures varied linearly with T-state mole fra...

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Detalles Bibliográficos
Autores principales: Belcher, Donald Andrew, Banerjee, Uddyalok, Baehr, Christopher Michael, Richardson, Kristopher Emil, Cabrales, Pedro, Berthiaume, François, Palmer, Andre Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636107/
https://www.ncbi.nlm.nih.gov/pubmed/29020036
http://dx.doi.org/10.1371/journal.pone.0185988