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Mixtures of tense and relaxed state polymerized human hemoglobin regulate oxygen affinity and tissue construct oxygenation
Pure tense (T) and relaxed (R) quaternary state polymerized human hemoglobins (PolyhHbs) were synthesized and their biophysical properties characterized, along with mixtures of T- and R-state PolyhHbs. It was observed that the oxygen affinity of PolyhHb mixtures varied linearly with T-state mole fra...
Autores principales: | Belcher, Donald Andrew, Banerjee, Uddyalok, Baehr, Christopher Michael, Richardson, Kristopher Emil, Cabrales, Pedro, Berthiaume, François, Palmer, Andre Francis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636107/ https://www.ncbi.nlm.nih.gov/pubmed/29020036 http://dx.doi.org/10.1371/journal.pone.0185988 |
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