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Treatment with high-dose antidepressants severely exacerbates the pathological outcome of experimental Escherichia coli infections in poultry

There is an urgent need for novel antibiotics as the current antibiotics are losing their value due to increased resistance among clinically important bacteria. Sertraline, an on-marked anti-depressive drug, has been shown to modify bacterial activity in vitro, including increasing the susceptibilit...

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Detalles Bibliográficos
Autores principales: Kromann, Sofie, Kudirkiene, Egle, Li, Lili, Thoefner, Ida, Daldorph, Elisabeth, Christensen, Jens Peter, Meng, Hecheng, Olsen, Rikke Heidemann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636113/
https://www.ncbi.nlm.nih.gov/pubmed/29020098
http://dx.doi.org/10.1371/journal.pone.0185914