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Diacetylenic lipids in the design of stable lipopolymers able to complex and protect plasmid DNA

Different viral and non-viral vectors have been designed to allow the delivery of nucleic acids in gene therapy. In general, non-viral vectors have been associated with increased safety for in vivo use; however, issues regarding their efficacy, toxicity and stability continue to drive further resear...

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Detalles Bibliográficos
Autores principales: Temprana, C. Facundo, Prieto, M. Jimena, Igartúa, Daniela E., Femia, A. Lis, Amor, M. Silvia, Alonso, Silvia del Valle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636127/
https://www.ncbi.nlm.nih.gov/pubmed/29020107
http://dx.doi.org/10.1371/journal.pone.0186194