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Diacetylenic lipids in the design of stable lipopolymers able to complex and protect plasmid DNA
Different viral and non-viral vectors have been designed to allow the delivery of nucleic acids in gene therapy. In general, non-viral vectors have been associated with increased safety for in vivo use; however, issues regarding their efficacy, toxicity and stability continue to drive further resear...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636127/ https://www.ncbi.nlm.nih.gov/pubmed/29020107 http://dx.doi.org/10.1371/journal.pone.0186194 |