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Efficient measurement and factorization of high-order drug interactions in Mycobacterium tuberculosis

Combinations of three or more drugs are used to treat many diseases, including tuberculosis. Thus, it is important to understand how synergistic or antagonistic drug interactions affect the efficacy of combination therapies. However, our understanding of high-order drug interactions is limited becau...

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Detalles Bibliográficos
Autores principales: Cokol, Murat, Kuru, Nurdan, Bicak, Ece, Larkins-Ford, Jonah, Aldridge, Bree B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636204/
https://www.ncbi.nlm.nih.gov/pubmed/29026882
http://dx.doi.org/10.1126/sciadv.1701881