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Proteins regulating the intercellular transfer and function of P-glycoprotein in multidrug-resistant cancer

Chemotherapy is an essential part of anticancer treatment. However, the overexpression of P-glycoprotein (P-gp) and the subsequent emergence of multidrug resistance (MDR) hampers successful treatment clinically. P-gp is a multidrug efflux transporter that functions to protect cells from xenobiotics...

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Detalles Bibliográficos
Autores principales: Pokharel, Deep, Roseblade, Ariane, Oenarto, Vici, Lu, Jamie F, Bebawy, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636210/
https://www.ncbi.nlm.nih.gov/pubmed/29062386
http://dx.doi.org/10.3332/ecancer.2017.768