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Proteins regulating the intercellular transfer and function of P-glycoprotein in multidrug-resistant cancer
Chemotherapy is an essential part of anticancer treatment. However, the overexpression of P-glycoprotein (P-gp) and the subsequent emergence of multidrug resistance (MDR) hampers successful treatment clinically. P-gp is a multidrug efflux transporter that functions to protect cells from xenobiotics...
Autores principales: | Pokharel, Deep, Roseblade, Ariane, Oenarto, Vici, Lu, Jamie F, Bebawy, Mary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cancer Intelligence
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636210/ https://www.ncbi.nlm.nih.gov/pubmed/29062386 http://dx.doi.org/10.3332/ecancer.2017.768 |
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