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Molecular determinants of permeation in a fluoride-specific ion channel
Fluoride ion channels of the Fluc family combat toxicity arising from accumulation of environmental F(-). Although crystal structures are known, the densely packed pore region has precluded delineation of the ion pathway. Here we chart out the Fluc pore and characterize its chemical requirements for...
Autores principales: | Last, Nicholas B, Sun, Senmiao, Pham, Minh C, Miller, Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636608/ https://www.ncbi.nlm.nih.gov/pubmed/28952925 http://dx.doi.org/10.7554/eLife.31259 |
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