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An acceptor analogue of β-1,4-galactosyltransferase: Substrate, inhibitor, or both?
Many glycosyltransferase inhibitors in the literature are structurally derived from the donor or acceptor substrate of the respective enzyme. A representative example is 2-naphthyl β-d-GlcNAc, a synthetic GlcNAc glycoside that has been reported as a galactosyltransferase inhibitor. This GlcNAc deriv...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636615/ https://www.ncbi.nlm.nih.gov/pubmed/28910600 http://dx.doi.org/10.1016/j.carres.2017.08.012 |