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Denervated muscle fibers induce mitochondrial peroxide generation in neighboring innervated fibers: Role in muscle aging

Disruption of neuromuscular junctions and denervation of some muscle fibers occurs in ageing skeletal muscle and contribute to loss of muscle mass and function. Aging is associated with mitochondrial dysfunction and loss of redox homeostasis potentially occurs through increased mitochondrial generat...

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Detalles Bibliográficos
Autores principales: Pollock, Natalie, Staunton, Caroline A., Vasilaki, Aphrodite, McArdle, Anne, Jackson, Malcolm J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636617/
https://www.ncbi.nlm.nih.gov/pubmed/28739532
http://dx.doi.org/10.1016/j.freeradbiomed.2017.07.017