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Denervated muscle fibers induce mitochondrial peroxide generation in neighboring innervated fibers: Role in muscle aging
Disruption of neuromuscular junctions and denervation of some muscle fibers occurs in ageing skeletal muscle and contribute to loss of muscle mass and function. Aging is associated with mitochondrial dysfunction and loss of redox homeostasis potentially occurs through increased mitochondrial generat...
Autores principales: | Pollock, Natalie, Staunton, Caroline A., Vasilaki, Aphrodite, McArdle, Anne, Jackson, Malcolm J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636617/ https://www.ncbi.nlm.nih.gov/pubmed/28739532 http://dx.doi.org/10.1016/j.freeradbiomed.2017.07.017 |
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