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Toll-like receptor 4 (TLR4) deficient mice are protected from adipose tissue inflammation in aging

Adipose tissue (AT) inflammation is a central mechanism for metabolic dysfunction in both diet-induced obesity and age-associated obesity. Studies in diet-induced obesity have characterized the role of Fetuin A (Fet A) in Free Fatty Acids (FFA)-mediated TLR4 activation and adipose tissue inflammatio...

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Detalles Bibliográficos
Autores principales: Ghosh, Amiya K., O'Brien, Martin, Mau, Theresa, Yung, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636669/
https://www.ncbi.nlm.nih.gov/pubmed/28898202
http://dx.doi.org/10.18632/aging.101288