The glucocorticoid receptor in monocyte-derived macrophages is critical for cardiac infarct repair and remodeling

Cell- and tissue-specific actions of glucocorticoids are mediated by the glucocorticoid receptor. Here, we demonstrate that the glucocorticoid receptor (GR) in macrophages is essential for cardiac healing after myocardial infarction. Compared with GR(flox) (wild-type controls), GR(LysMCre) mice that...

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Detalles Bibliográficos
Autores principales: Galuppo, Paolo, Vettorazzi, Sabine, Hövelmann, Julian, Scholz, Claus-Jürgen, Tuckermann, Jan Peter, Bauersachs, Johann, Fraccarollo, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636710/
https://www.ncbi.nlm.nih.gov/pubmed/28768721
http://dx.doi.org/10.1096/fj.201700317R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636710/
https://www.ncbi.nlm.nih.gov/pubmed/28768721
http://dx.doi.org/10.1096/fj.201700317R

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