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NADPH Oxidase Mediates β-Amyloid Peptide-Induced Neuronal Death in Mouse Cortical Cultures

β-Amyloid peptide (Aβ) is the main component of senile plaques in patients with Alzheimer's disease, and is known to be a main pathogenic factor of the disease. Recent evidence indicates that activation of NADPH oxidase (NOX) in microglia or astrocytes may be a source of Aβ-induced reactive oxy...

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Detalles Bibliográficos
Autores principales: Chay, Kee-Oh, Nam Koong, Kyoung Young, Hwang, Shinae, Kim, Jong-Keun, Bae, Choon Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chonnam National University Medical School 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636758/
https://www.ncbi.nlm.nih.gov/pubmed/29026707
http://dx.doi.org/10.4068/cmj.2017.53.3.196