Cargando…
The quaternary architecture of RARβ–RXRα heterodimer facilitates domain–domain signal transmission
Assessing the physical connections and allosteric communications in multi-domain nuclear receptor (NR) polypeptides has remained challenging, with few crystal structures available to show their overall structural organizations. Here we report the quaternary architecture of multi-domain retinoic acid...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636793/ https://www.ncbi.nlm.nih.gov/pubmed/29021580 http://dx.doi.org/10.1038/s41467-017-00981-y |