Danshenol A inhibits TNF-α-induced expression of intercellular adhesion molecule-1 (ICAM-1) mediated by NOX4 in endothelial cells

ICAM-1 overexpression and subsequent adhesion of leukocytes to endothelial cells play critical roles in the early stage of atherosclerosis. Danshenol A (DA) is an abietane-type diterpenoid isolated from traditional Chinese herb Salvia miltiorrhiza Bunge. The mechanisms under its regulation of adhesi...

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Detalles Bibliográficos
Autores principales: Zhao, Wenwen, Feng, Haitao, Guo, Shuhui, Han, Yantao, Chen, Xiuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636799/
https://www.ncbi.nlm.nih.gov/pubmed/29021525
http://dx.doi.org/10.1038/s41598-017-13072-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636799/
https://www.ncbi.nlm.nih.gov/pubmed/29021525
http://dx.doi.org/10.1038/s41598-017-13072-1

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