Mortalin deficiency suppresses fibrosis and induces apoptosis in keloid spheroids

Mortalin (Mot) is a mitochondrial chaperone of the heat shock protein 70 family and it’s pro-proliferative and anti-apoptosis functions could be associated with keloid pathogenesis, and blocking of mortalin and its interaction with p53 might be a potential novel target for the treatment of keloid. T...

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Detalles Bibliográficos
Autores principales: Lee, Won Jai, Ahn, Hyo Min, Na, Youjin, Wadhwa, Renu, Hong, JinWoo, Yun, Chae-Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636810/
https://www.ncbi.nlm.nih.gov/pubmed/29021584
http://dx.doi.org/10.1038/s41598-017-13485-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636810/
https://www.ncbi.nlm.nih.gov/pubmed/29021584
http://dx.doi.org/10.1038/s41598-017-13485-y

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