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Mortalin deficiency suppresses fibrosis and induces apoptosis in keloid spheroids
Mortalin (Mot) is a mitochondrial chaperone of the heat shock protein 70 family and it’s pro-proliferative and anti-apoptosis functions could be associated with keloid pathogenesis, and blocking of mortalin and its interaction with p53 might be a potential novel target for the treatment of keloid. T...
Autores principales: | Lee, Won Jai, Ahn, Hyo Min, Na, Youjin, Wadhwa, Renu, Hong, JinWoo, Yun, Chae-Ok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636810/ https://www.ncbi.nlm.nih.gov/pubmed/29021584 http://dx.doi.org/10.1038/s41598-017-13485-y |
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